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The principal cytochrome P450 isoenzyme included seems to become CYP2E1, with CYP1A2 and CYP3A4 as further pathways. Roughly eighty five% of an oral dose appears during the urine within 24 hours of administration, most as being the glucuronide conjugate, with small amounts of other conjugates and unchanged drug.Embryo-Fetal Toxicity Tell feminine p